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1.

What is botulinum toxin and how does it work? How do you prepare a vial for injections (solution, dilution)? What is the shelf-life? How long does it last?

Reference(s):

Trindade De Almeida, A. R., Secco, L. C., & Carruthers, A. (2011). Handling botulinum toxins: an updated literature review. Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.], 37(11), 1553–1565.

2.

List FDA approved indications for its use in the H&N.  What are common off-label uses?

3.

Give us the low-down on Botox……what are the various commercially available forms? Is one “better” than the other?

Reference(s):

Walker, T.J., Dayan, S.H. (2014). Comparison and overview of currently available neurotoxins. J Clin Aesthet Dermatol, 7(2), 31-9.

Wilson, A.J., Chang, B, Taglienti, A.J., Chin, B.C., et al. A quantitative analysis of onabotulinumtoxinA, AbobotulinumtoxinA, and IncobotulinumtoxinA: A randomized, double-blind, prospective clinical trial of comparative dynamic strain reduction. Plast Reconstr Surg, 137(5), 1424-33.

4.

Are there any adverse events associated with botulinum toxin?

5.

Hilary Clinton wants to get rid of her crows feet, glabellar lines and forehead wrinkles. She wants all the details on technique and how much botox you plan to inject.

6.

What is Restalyne?  How effective is it as an injectable filling agent in the face?

Reference(s):

Rohrich, R. J., Ghavami, A., & Crosby, M. A. (2007). The role of hyaluronic acid fillers (Restylane) in facial cosmetic surgery: review and technical considerations. Plastic and Reconstructive Surgery, 120(6 Suppl), 41S–54S.

7.

Tell us about the soft tissue filler Radiesse. How does it compare to Restalyne?  How effective is it in mid and lower face rejuvenation?

Reference(s):

Fakhre, G.P., Perdikis, G, Shaddix, K.K., Terkonda, S.P., et al. (2009). An evaluation of calcium hydroxylapatite (Radiesse) for cosmetic nasolabial fold correction: a meta-analysis and patient centric outcomes study. Ann Plast Surg, 63(5), 486-9.

Gravier,M.H., Bass, L.S., Busso, M., Jasin, M.E., et al. (2007). Calcium hydroxylapatite (Radiesse) for correction of the mid- and lower face: consensus recommendations. Plast Reconstr Surg, 120(6): 55s-66s.

8.

Angelina Jolie wants fillers to correct her nasolabial folds. What are the  potential complications of fillers.

Reference(s):

Beleznay, K, Carruthers, J.D., Humphrey, S, Jones, D. (2015). Avoiding and treating blindness from fillers: a review of the world literature. Dermatol Surg, 41(10), 1097-117.

Scheuer, J.F. 3rd, Sieber, D.A., Pezeshk, R.A., Campbell, C.F., et al. (2017). Anatomy of the facial danger zones: maximizing safety during soft-tissue filler injections. Plast Reconstr Surg, 139(1), 50e-58e.

9.

Does anyone use collagen anymore?

Reference(s):

Matarasso, S.L. (2007). Injectable collagens: lost but not forgotten- a review of products, indications, and injection techniques. Plast Reconstr Surg, 120(6 suppl), 17S-26S.

Lucey, P, Goldberg, D.J. (2014). Complications of collagen fillers. Facial Plast Surg, 30(6), 615-22.

10.

Fat grafting and facial rejuvenation.

Reference(s):

Glasgold, M., Glasgold, R., & Lam, S. (2015). Autologous fat grafting for midface rejuvenation. Clinics in Plastic Surgery, 42(1), 115–121.