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1.

What are the ABCD’s of melanoma screening?

2.

What are the risk factors for melanoma?

3.

Why is the incidence of melanoma rising?

4.

Comment on the benign cousins of melanoma i.e.: junctional nevi, compound nevi, blue nevi, spitz nevi, liver spots.

5.

Discuss melanoma precursors: lentigo maligna, dysplastic nevi.

6.

Tell us about the 4 different types of cutaneous melanoma and their growth patterns.

7.

Review the new 8th edition AJCC TNM staging system for cutaneous melanoma. What are the important histologic factors? Is invasion still relevant? How is the mitotic rate used as a prognostic factor? What is the survival rate for each stage? What is the difference between Clark and Breslow?

8.

Discuss prognostic factors in melanoma.

9.

How does an elevated serum LDH predict survival?

10.

What margins are needed when excising melanoma?

11.

A patient presents with a concerning skin lesion on the forehead. How would you biopsy this lesion – excisional, incisional, punch?

12.

There exists controversy about the role of sentinel lymph node biopsy in the staging of H&N melanoma. Is it accurate? What are the prognostic implications? Who should get it?

Reference(s):

Kupferman, M. E., Kubik, M. W., Bradford, C. R., Civantos, F. J., Devaney, K. O., Medina, J. E., … Ferlito, A. (2014). The role of sentinel lymph node biopsy for thin cutaneous melanomas of the head and neck. American Journal of Otolaryngology, 35(2), 226–232.

13.

Who gets an elective neck dissection?

14.

Provide us with a table of available adjuvant therapies and include indications and outcomes.

15.

Tell us about pembrolizumab. What do we otolaryngologists need to know in order to refer patients for this medication?