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Read the following publication: Seidman, M.D., Gurgel, R.K., Lin, S.Y., Schwartz, S.R., et al.(2015). Clinical Practice Guideline: Allergic Rhinitis. Otolaryngol Head Neck Surg, 152(1), S1-S43.

Basic Immunology:

1.

What are the direct and indirect Coombs tests?

2.

What are the different types of hypersensitivity reactions? Give examples of each?

3.

What are the different immunoglobulin types and what is their typical structure?

4.

Role of inflammatory cells and mediators involved in allergic rhinitis?

5.

Tell us about congenital immunodeficiency syndromes

6.

Review humoral vs. cell-mediated immunity. What are natural killer cells?

Allergy Testing:

7.

Describe different types of allergy testing (in vivo and in vitro); pros and cons of each.

8.

Describe MQT and how it is used.

Allergy Treatment:

9.

What are the common allergens (perennial vs. seasonal) and the times of year that patients are most affected?

10.

How would you advise a patient on environmental control?

11.

Educate us on immunotherapy…SET vs. RAST based treatment.

12.

Discuss SLIT vs SCIT. What are the current indications for SLIT? Is it effective? Is it safe?

Reference(s):

Honda, T, Normura, T, Kabashima, K. (2017). Advances in atopic dermatitis and urticarial in 2016. J Allergy Clin Immunol, 140(2), 369-376.

Lin, S.Y., Erekosima, N., Kim, J.M., Ramanathan, M., et al. (2013). Sublingual immunotherapy for the treatment of allergic rhinoconjunctivitis and asthma: a systematic review. JAMA, 309(12), 1278-88.

Other:

13.

Define and manage anaphylactic shock. Compare and contrast symptoms/treatment with vasovagal response.

14.

List common head and neck manifestations of allergic disease.